Silica sheets to deliver DNA into cells for disease prevention and treatment

Scientists in Japan have made a new DNA delivery substrate based on networks of bio-friendly upright silica sheets. The network of sheets forms a porous film on to which they can immobilise DNA, ready for delivery (transfection) into cells. The transfection efficiency of the silica film is approximately double that of solution-based transfection. Gene transfection is a potential method for preventing and treating diseases and analysing cell functions.

 

Silica sheets to deliver DNA into cells for disease prevention and treatment

Link to journal article
Silica-based Gene Reverse Transfection: Upright Nanosheet Network for Promoted DNA Delivery to Cell

Q Ji et al

Chem. Commun., 2012, DOI: 10.1039/c2cc34289h

 

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