Archive for the ‘Themed Issue’ Category

Open Call for Papers: Novel Biomedical Polymer Materials

Open Call for Papers: Novel Biomedical Polymer Materials

Guest Edited by Professor Huayu Tian and Professor Xuesi Chen

 

We are delighted to announce a special themed collection on Novel Biomedical Polymer Materials to be published across Biomaterials Science  and Journal of Materials Chemistry B. This collection is Guest Edited by:

Professor Huayu Tian (Xiamen University)

Professor Xuesi Chen (Changchun Institute of Applied Chemistry, University of the Chinese Academy of Sciences)

Submissions Deadline: 1 November 2023

Biomedical polymer materials, as materials for diagnosis, treatment and organ regeneration, have the mission of prolonging patients’ lives and improving their quality of life. Their research occupies a very important position in the fields of biotechnology, life sciences and medicine, and different fields of biomedicine have different requirements for biomedical materials. Thus, in order to promote the development of the medical field, the synthesis of new biomaterials is of great significance.

To this end, this themed collection in Journal of Materials Chemistry B and Biomaterials Science aims at providing a platform for recent developments in this rapidly evolving field and we encourage you to submit your latest research to feature in the collection.

Submissions to the journal should fit within the scope of Journal of Materials Chemistry B or Biomaterials Science – Please see the journal’s website for more information on the journal’s scope, standards, article types and author guidelines. You may submit to whichever journal you feel is most relevant to your current research. Please note that your article may be offered a transfer to the alternate journal if deemed more appropriate by the handling Editor. Articles that primarily focus on providing insight into the underlying science and performance of biomaterials within a biological environment are more suited to Biomaterials Science. whereas articles that primarily focus on demonstrating novel materials chemistry and bring a molecular picture on a given material’s suitability as a biomaterial are more suited to Journal of Materials Chemistry B.

For this collection, we strongly encourage full primary research in the way of Full Papers or Communications.

All manuscripts must be in scope for the journal and will undergo the normal initial assessment and peer review processes in line with the journal’s high standards, managed by the journal editors. Accepted manuscripts will be added to the online collection as soon as they are published and they will be featured in a regular issue of the relevant journal.

If you would like to contribute to this themed collection, please submit your article directly through the Biomaterials Science submission service or the Journal of Materials Chemistry B submission service. Please mention that your submission is a contribution to the Novel Biomedical Polymer Materials collection in the “Themed issues” section of the submission form and add a “Note to the Editor” that this is from the Open Call. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of both the journal and the collection, and as such inclusion of accepted articles in the final themed collection is not guaranteed. All submissions will be subject to initial assessment and sent for peer review, if appropriate. We cannot guarantee peer review or acceptance of your submission in the journal.

If you have any questions about the collection or the submissions process, please do contact the Editorial Office at biomaterialsscience-rsc@rsc.org and they will be able to assist.

We look forward to receiving your latest work and considering it for this collection!

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Call for papers: Injectable Hydrogels

Call for papers: Injectable Hydrogels

Guest Edited by Dr Khoon Lim and Dr Julieta Paez

We are delighted to announce a special themed collection on Injectable Hydrogels to be published across Biomaterials Science  and Journal of Materials Chemistry B. This collection is Guest Edited by:

Dr Khoon Lim (University of Sydney, Australia)

Dr Julieta I Paez (University of Twente, The Netherlands)

Injectable hydrogels have emerged as intelligent and versatile materials that have been proven to possess huge potential for many biomedical applications including drug delivery, tissue engineering, and regenerative medicine. Hydrogels are a class of polymers with highly hydrated 3D networks that have microenvironmental properties such as oxygen/nutrient permeability that are similar to the native extracellular matrix. In addition to possessing the typical advantages of conventional hydrogels, injectable hydrogels offer an extra unique feature, which enables minimally invasive injectability and durability for irregularly shaped sites. As such, there has been a growing interest of using injectable hydrogels as scaffolds/carriers for therapeutic agents, including but not limited to drugs, cells, proteins, and bioactive molecules, targeted to treat chronic diseases including cancer, but also to facilitate the repair and regeneration of damaged organs/tissues.

In this context, it is pertinent to compile this themed collection focusing on recent rapid development in the field of injectable hydrogels. To this end, this themed collection in Journal of Materials Chemistry B and Biomaterials Science aims at providing a platform for recent developments in this rapidly evolving field of injectable hydrogels including, but not limited to:

  • Emerging chemistries
  • Synthesis pathways
  • Fabrication methods
  • Cell-material interactions
  • In vitro and in vivo performances
  • Targeted applications (drug delivery, tissue engineering and regenerative medicine)

Submissions to the journal should fit within the scope of Journal of Materials Chemistry B or Biomaterials Science – Please see the journal’s website for more information on the journal’s scope, standards, article types and author guidelines. We encourage you to submit your work to the journal you feel is most appropriate.

For this collection, we strongly encourage full primary research in the way of Full Papers or Communications.

 

Submission Deadline: 10 September 2023

If you would like to contribute to this themed collection, please submit your article directly through the Biomaterials Science submission service or the Journal of Materials Chemistry B submission service. Please mention that your submission is a contribution to the Injectable Hydrogels collection in the “Themed issues” section of the submission form and add a “Note to the Editor” that this is from the Open Call. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of both the journal and the collection, and as such inclusion of accepted articles in the final themed collection is not guaranteed. All submissions will be subject to initial assessment and sent for peer review, if appropriate. We cannot guarantee peer review or acceptance of your submission in the journal.

If you have any questions about the collection or the submissions process, please do contact the Editorial Office at materialsb-rsc@rsc.org and they will be able to assist.

We look forward to receiving your latest work and considering it for this collection!

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Open Call for Microneedles themed collection: Meet the Guest Editors

Biomaterials Science and companion journal Journal of Materials Chemistry B are pleased to announce an open call for submissions to a cross-journal themed collection on ‘Microneedles’.

This cross-journal themed collection on ‘Microneedles’ aims to bring together recent advancements in the field of microneedles that readers will find informative and useful. The topics could include microneedle fabrication and development approaches, applications of microneedles that add a new dimension to existing core knowledge in the microneedles field, sensing applications and clinical studies that evaluate efficacy or other aspects of microneedle use in humans.

The Guest Editors for this themed collection are: Ester Caffarel-SalvadorRyan DonnellyHarvinder Gill and Hyungil Jung

 

Find out more about the Guest Editors below:

 

Dr Ester Caffarel-Salvador
Scientific Consultant, USA

‘Microneedles are no longer confined to transdermal drug delivery, they are also being used to deliver drugs to organs such as the eye and the gastrointestinal tract as well as for drug monitoring applications. I am particularly excited to see how microneedles are being employed in novel devices to help overcome the challenges of oral delivery of biologics.’

Dr. Ester Caffarel-Salvador is a multidisciplinary scientist with a background in biotechnology and biochemistry. At MIT, she developed a pill to administer insulin orally, now in clinical trials, which led the MIT Technology Review to recognize her as one of the 35 Innovators Under 35 in 2019.

After taking a mini-MBA at Harvard and working across startups, VCs, consulting, and pharmaceutical companies, Ester is now the Associate Director of Strategic Innovation for Rare Diseases at Chiesi USA. She is also a lecturer at MIT and an advisor to several startups. Ester speaks seven languages and is passionate about advocating on career development for women in science.

 

 Prof. Ryan Donnelly
Queen’s University Belfast, UK

‘Why microneedles? Microneedles are one of the fastest growing areas of innovation in drug and vaccine delivery today. They offer the possibility of needle-free delivery of currently injectable medicines that could help overcome the COVID-induced backlog in healthcare provision globally. In developing countries needle-free vaccine administration would improve access to safe and effective vaccines for millions of people.’

Professor Ryan Donnelly holds the Chair in Pharmaceutical Technology at Queen’s University Belfast and is Director of QUB’s interdisciplinary research programme Materials & Advanced Technologies for Healthcare (MATCH). His personal research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and intradermal drug delivery, with a strong emphasis on improving patient outcomes. He is currently developing a range of novel microneedle technologies through independent research, but also in collaboration with several major pharma partners. He has obtained substantial UK Research Council, charity and industrial funding and authored over 600 peer-reviewed publications (H-index = 73), including 6 patent applications, 6 textbooks, 23 book chapters and approximately 300 full papers. He has been an invited speaker at numerous national and international conferences. Professor Donnelly is Europe/Africa Editor of Drug Delivery & Translational Research and the Controlled Release Society’s Communications Chair. He has won the Academy of Pharmaceutical Science’s Innovative Science Award (2020), the Controlled Release Society’s Young Investigator Award (2016), BBSRC Innovator of the Year and the American Association of Pharmaceutical Scientists Pharmaceutical Research Meritorious Manuscript Award (2013 and 2022), the GSK Emerging Scientist Award (2012) and the Royal Pharmaceutical Society’s Science Award (2011).

 

 

Prof. Harvinder Gill
Texas Tech University, USA

‘The first microneedle paper was published in 1998. I am thrilled at this opportunity to co-edit a joint themed edition for Journal of Materials Chemistry B and Biomaterials Science to showcase the achievements that have been made in the field over the past nearly 25 years. By pairing these two journals for the themed edition, we have a unique opportunity of highlighting both the materials and manufacturing aspects, and the biological applications aspects of microneedles. I look forward to reading the outstanding work in the field from colleagues around the world.’

Dr. Gill is a Professor of Chemical Engineering at Texas Tech University, Lubbock, TX, USA. His research interests are in the fields of immunoengineering and micro-nano medicine. He has expertise in delivery systems such as microneedles, pollen grains, polymeric micro-nano particles, and gold nanoparticles. He has a history of innovativeness, and of providing fresh and unique perspectives to research and medical problems. Dr. Gill is working towards the development of a universal influenza vaccine using nanoparticle systems to enhance vaccine efficacy. He is amongst the pioneers of microneedle technology and has produced seminal work in the field. He was also the first to propose use of pollen grains as “Trojan horses” for oral vaccination and has published original and seminal papers in this field, which has attracted other researchers. He is also the pioneer of the use of microneedles for allergen immunotherapy and his lab is currently developing microneedles for the treatment of airway and peanut allergen immunotherapies. This technology is being commercialized through a startup company called Moonlight Therapeutics, which Dr. Gill has co-founded.

Dr. Gill completed his Bachelor of Engineering in Chemical Engineering with honors and a gold medal from Panjab University, India (1994). After graduation, he worked in the petroleum industry for seven years. Subsequently he obtained his doctoral degree in Bioengineering from Georgia Institute of Technology (2007). Dr. Gill received his postdoctoral training in the field of influenza vaccines at Emory University (2009). Dr. Gill has received numerous awards and honors, including the prestigious NIH Director’s New Innovator Award (DP2 award) and Defense Advanced Research Projects Agency (DARPA) Young Faculty Award for his pollen research, Chancellor’s Council Distinguished Research Award, Barney E. Rushing, Jr. Faculty Distinguished Research Award STEM, Ed and Linda Whitaker Faculty Fellow Award, and Whitacre Engineering Research Award. For his accomplishments and contributions to Biomedical Engineering, he was awarded the Whitacre Endowed Professorship in Science and Engineering at Texas Tech.

 

Prof. Hyungil Jung
Yonsei University, Korea

‘Microneedles are truly an exciting platform for next generation drug delivery’

Hyungil Jung is a Professor in the Department of Biotechnology at Yonsei University, where he is also the Chair of the Bio & Living Engineering Major in Global Leaders College, as well as Director of the Institute of Bio-Medical Health Care Convergence and the Department Head of Integrative Biotechnology & Translational Medicine. He is also the founder and CSO of JUVIC Inc., a company developing microneedle-based products. He received his B.S. and M.S. from Yonsei University in 1993 and 1995, and his Ph.D. from Cornell University in 2002. He worked at Caltech as a Postdoctoral scholar from 2002 through 2004 and then joined Yonsei University at 2004. His main interests lie in commercialization of microneedles and overcoming the pressing challenges in microneedle development for commercialization. During his spare time, his hobby is indulging in board games, his favorite being Baduk, a widely popular traditional board game in Korea.

 

Submissions for this themed collection are open until 1 March 2023

 

The call for papers is open for the following article types:

  • Communications
  • Full papers
  • Reviews
  • Perspectives

 

If you would like to submit to this themed collection, you can submit your article directly to the online submission platform for Journal of Materials Chemistry B or Biomaterials Science. Please mention that this submission is a contribution to the Microneedles collection in the “Themed issues” section of the submission form and add a “Note to the Editor” that this is from the Open Call. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of both the journal and the collection, and inclusion of accepted articles in the final themed issue is not guaranteed.

Please note that all submissions will be subject to initial assessment by the journal editors and as such we cannot guarantee peer review or final acceptance of your manuscript. If you have any questions about the collection, email us at materialsb-rsc@rsc.org.  We look forward to receiving and featuring your submissions in this exciting collection!

 

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Open call for papers: Themed collection on Microneedles

Biomaterials Science is delighted to announce an open call for submissions to a cross-journal themed collection on ‘Microneedles’ with companion journal Journal of Materials Chemistry B.

Guest edited by Dr Ester Caffarel-Salvador (Scientific Consultant, USA) Professor Ryan Donnelly (Queen’s University Belfast, UK), Professor Harvinder Gill (Texas Tech, USA) and Professor Hyungil Jung (Yonsei University, Korea).

 

Submissions open until 1 March 2023

 

Microneedles, since their inception as a unique transdermal drug and vaccine delivery system, have become a noteworthy system used in multiple routes, including gastrointestinal, oral (mouth cavity) and ocular, to name a few. The range of illnesses being targeted by microneedles has also increased significantly and includes infectious diseases, pain, diabetes, and allergies for example. Sensing is another upcoming application of microneedles. Innovation in microneedle fabrication continues to not only push the drug-carrying and delivering capacity of microneedles, but also making mass manufacturing feasible and economical. There is also increased activity in the commercial sector with different companies attempting to bring the first microneedle-based medical device to market.

This cross-journal themed collection on ‘Microneedles’ in Journal of Materials Chemistry B and Biomaterials Science aims to bring together recent advancements in the field of microneedles that readers will find informative and useful. The topics could include microneedle fabrication and development approaches, applications of microneedles that add a new dimension to existing core knowledge in the microneedles field, sensing applications and clinical studies that evaluate efficacy or other aspects of microneedle use in humans.

Submissions to the journal should fit within the scope of Journal of Materials Chemistry B or Biomaterials Science – Please see the journal website for more information on the journal’s scope, standards, article types and author guidelines. We encourage you to submit your work to the journal that you feel best reflects the scope of your work.

The call for papers is open for the following article types:

  • Communications
  • Full papers
  • Reviews
  • Perspectives

 

If you would like to submit to this themed collection, you can submit your article directly to the online submission platform for Journal of Materials Chemistry B or Biomaterials Science. Please mention that this submission is a contribution to the Microneedles collection in the “Themed issues” section of the submission form and add a “Note to the Editor” that this is from the Open Call. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of both the journal and the collection, and inclusion of accepted articles in the final themed issue is not guaranteed.

Please note that all submissions will be subject to initial assessment by the journal editors and as such we cannot guarantee peer review or final acceptance of your manuscript. If you have any questions about the collection, email us at biomaterialsscience-rsc@rsc.org.  We look forward to receiving and featuring your submissions in this exciting collection!

 

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European Society for Biomaterials: 31st Annual Conference collection and upcoming 32nd Annual Conference

As the official journal of the European Society for Biomaterials (ESB), Biomaterials Science has worked in partnership with the ESB to highlight some of the most interesting research from the community on the conference topic of ‘Future with Biomaterials’.

The 31st Annual Conference of the European Society for Biomaterials (ESB 2021) took place virtually from September 5 to 9, 2021. Guest Editors selected authors who presented some of the most interesting research and they were invited to submit a paper to the journal.

We are excited to highlight our collection showcasing some of the best research that was presented at ESB2021. All articles are free to read until the 2nd October 2022.

Read the collection here: https://rsc.li/esb-2021

 

The 32nd Annual Conference of the European Society for Biomaterials

Biomaterials Science is pleased to be sponsoring the 32nd Annual Conference of the European Society for Biomaterials (ESB2022) to be held in Bordeaux on 3-8 September 2022.

Come and watch our 2022 Lectureship winner Yizhou Dong from Ohio State University, USA giving his lectureship talk in Room A on Monday 5 September at 5.15pm

 

Come and Meet the team!

Biomaterials Science Deputy Editor Laura Ghandhi and Merlin Fox from the RSC books team will be attending ESB2022. Come visit the ESB stand in the main Exhibition Hall throughout the conference and ask any questions you have about Biomaterials Science or the RSC.

 

We hope you enjoy reading the collection and look forward to seeing some of you in Bordeaux for ESB2022!

 

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Call for papers: CRISPR biomaterials

 

Biomaterials Science is delighted to announce a call for papers for its latest themed collection on “CRISPR biomaterials” Guest Edited by Yuan Ping (Zhejiang University), Ming Wang (Institute of Chemistry, Chinese Academy of Sciences) and Qiaobing Xu (Tufts University). 

 

You can access the online collection here to look at the first few contributions to this collection.

 

The shortage of delivery biomaterials that can deliver genome editors and control editing activities represents one of the major challenges for successful CRISPR/Cas-based genome editing. This collection on CRISPR biomaterials seeks to fuel the development in the field of biomaterials for CRISPR/Cas-based genome editing components, and provide a comprehensive overview of the emerging delivery technologies and recent progresses for exploiting biomaterials for CRISPR/Cas systems. We aim to cover the principles of biomacromolecule delivery and gene editing, examine recent advances and challenges in both non-viral and viral delivery methods, and exemplify the status of related applications and clinical trials. The current challenges and future prospects of the delivery technologies for CRISPR system for clinical translations will also discussed.

 

Manuscripts should be submitted via the Royal Society of Chemistry’s online submission service available at https://mc.manuscriptcentral.com/bmsci and let us know by email to biomaterialsscience-rsc@rsc.org. Please add a “note to the editor” in the submission form when you submit your manuscript to say that this is a submission for the themed collection. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of the collection and inclusion of accepted articles in the collection is not guaranteed. Please see our website for more information on journal scope, standards, article types and author guidelines.

 

All manuscripts will be subject to the journal’s usual peer review process. Accepted manuscripts will be added to the online collection as soon as they are online and they will be published in a regular issue of Biomaterials Science.

 

If you have any questions about the journal or the collection, then please do contact the Editorial Office at biomaterialsscience-rsc@rsc.org.

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Profile: Matt Webber, 2017 Biomaterials Science Emerging Investigator

Profile: Matt Webber, 2017 Biomaterials Science Emerging Investigator

This week’s issue of Biomaterials Science is our 2019 Emerging Investigators issue, which contains reviews and research articles from biomaterials scientists in the early stages of their independent careers. The 2019 Biomaterials Science Emerging Investigators were individually nominated by members of the journal Editorial and Advisory Boards, and previous Emerging Investigators, in recognition of their potential to influence future directions in the biomaterials field. The issue is accompanied by an Editorial from Editor-in-Chief Jennifer Elisseeff, which discusses some of the great work on display, and contains biographies and photos of the contributors.

In order to celebrate this issue, we are delighted to feature a profile of one of the researchers from our 2017 Emerging Investigators issue, Matt Webber. Matt talks below about how his research has progressed since being featured as a Biomaterials Science Emerging Investigator.

“It was a great honor to have been included as a 2017 Emerging Investigator. When I was selected for this honor, my team had not even moved into our lab space and I had just started my independent position. I was surprised people even knew who I was, but of course I accepted! We had access to a peptide synthesizer, and went about devising a project that would be possible to complete on a short timeline with limited resources. We begun by investigating the self-assembly of a series of tripeptides, which we designed to be amphiphilic with a variable residue positioned in the center of an aromatic group and a charged group. We thought some sequences might self-assemble, but in a stroke of pure serendipity we were fortunate to discover the emergence of 5 unique nanostructures from these five different sequences. This was very exciting, leading my group to continue to explore the self-assembly of minimal peptide sequences. This initial work published in Biomaterials Science resulted in a follow-up paper published in 2018 in Soft Matter and several other forthcoming works and invited presentations. Strangely enough, we may never have done this work or pursued this line of research if it were not for the opportunity to participate in the 2017 Emerging Investigator issue. I am grateful to Biomaterials Science for this honor, and for nucleating a great start to my research group.”

 

Biography
Matthew J. Webber is an Assistant Professor in the Department of Chemical & Biomolecular Engineering at the University of Notre Dame, with a concurrent appointment in the Department of Chemistry and Biochemistry. His research group is interested in applying supramolecular principles, leveraging defined and rationally designed non-covalent interactions, to improve therapeutic materials. He is specifically curious about the use of supramolecular design to overcome barriers in drug delivery and improve biomedical materials. Prof. Webber received a BS in Chemical Engineering from the University of Notre Dame, and MS and PhD degrees in Biomedical Engineering from Northwestern University. His dissertation, performed in the laboratory of Prof. Samuel Stupp, focused on the use supramolecular peptide assemblies for cardiovascular disease therapeutics. Subsequently, he was an NIH NRSA postdoctoral fellow in the laboratories of Prof. Robert Langer and Prof. Daniel Anderson at MIT, working on the development of new molecular engineering approaches toward the treatment of diabetes. His research passion is to contribute to bringing the field of Supramolecular Therapeutics into prominence. He has authored 56 peer-reviewed papers and is inventor on 7 pending or awarded patents. In 2017, he was named by Biomaterials Science as an Emerging Investigator and by the American Institute of Chemical Engineers (AIChE) as one of the “35 under 35” young leaders shaping the field.

Matt’s papers will be free to access on our publishing platform for 6 weeks.

We hope you enjoy reading all the contributions to our 2019 Emerging Investigators collection, and we thank all the nominators and authors for their input.

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Polymeric biomaterials for cancer nanotechnology themed issue now online

We are delighted to announce that the Polymeric biomaterials for cancer nanotechnology themed issue is now available online.

Polymeric biomaterials for cancer nanotechnology

Guest Edited by Jianjun Cheng (University of Illinois at Urbana-Champaign, USA) and Suzie H. Pun (University of Washington, USA), this themed issue highlights the latest discoveries and innovations in polymeric biomaterials for cancer nanotechnology.

Polymeric biomaterials have been extensively used in nanomedicine formulations for cancer therapy. Preclinical and clinical studies have in general revealed that polymeric nanocarriers, when used for chemotherapeutic drug delivery, reduce systemic toxicity and thus mitigate adverse side effects of the drug. This themed issue contains reviews and research articles in the areas of: (i) expanding the available suite of polymeric biomaterials that can be reproducibly and controllably manufactured at a suitable scale, (ii) designing carriers with improved biodistribution to tumour sites, (iii) increasing tumour distribution and penetration of polymeric nanocarriers, and (iv) controlling efficient drug release at a desired location and with optimal kinetics.

Read all the themed issue papers here

A few articles from the themed issue are highlighted below:

Drug-free macromolecular therapeutics – a new paradigm in polymeric nanomedicines
Te-Wei Chu and Jindřich Kopeček
Biomater. Sci., 2015,3, 908-922

Lipid-coated polymeric nanoparticles for cancer drug delivery
Sangeetha Krishnamurthy, Rajendran Vaiyapuri, Liangfang Zhang and Juliana M. Chan
Biomater. Sci., 2015, 3, 923-936

Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids
Hongxu Lu, Robert H. Utama, Uraiphan Kitiyotsawat, Krzysztof Babiuch, Yanyan Jiang and Martina H. Stenzel
Biomater. Sci., 2015, 3, 1085-1095

Polymeric assembly of hyperbranched building blocks to establish tunable nanoplatforms for lysosome acidity-responsive gene/drug co-delivery
Hui-Zhen Jia, Wei Zhang, Xu-Li Wang, Bin Yang, Wei-Hai Chen, Si Chen, Gang Chen, Yi-Fang Zhao, Ren-Xi Zhuo, Jun Feng and Xian-Zheng Zhang
Biomater. Sci., 2015,3, 1066-1077

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Themed collection for Michael Sefton’s 65th birthday

Nicholas Peppas (University of Texas) introduces our latest themed collection, put together in celebration of Michael Sefton’s 65th birthday.

I am delighted to express my thoughts on the occasion of this special collection in honor of Michael V. Sefton of the University of Toronto. Michael has been a friend for 44 years and has been a source of inspiration for several generations of biomaterials scientists, biomedical engineers, chemical engineers and polymer scientists.  He has been a leader in the fields of biomaterials, regenerative medicine and tissue engineering for the past 40 years.  Michael is recognized for seminal contributions to biomaterials science, regenerative medicine and tissue engineering, for development of novel methods for diabetes treatment and for visionary international leadership of the field of biomedical engineering.

Michael Sefton was born 65 years ago, on October 20, 1949, in London, United Kingdom. At a young age, the family left the UK and came to Canada where Michael, his brother and sister grew up in a loving family, always excelling. He entered the Chemical Engineering Department of the University of Toronto in 1967 and had the fortune to be educated by leading scientists in polymer science and artificial organs. This combination of the two areas led to his decision to pursue a graduate degree in chemical engineering, concentrating on biomaterials. So, we both arrived to the Massachusetts Institute of Technology (MIT) in August 1971 and we started working in the Chemical Engineering Department, he as a research assistant of Ken Smith, I as a volunteer in Ed Merrill’s laboratory. As all loyal students working on biomaterials those days did, we took courses such as 10.68 “Physical Chemistry of Polymers”, 10.64 “Structure and Properties of Polymers” and 10.69 “Polymerization Reactions”, along with 2.905 “Biomaterials” and the famous 10.56 “Chemical Engineering in Medicine”, the legendary course introduced to the curriculum 50 years ago by Ed Merrill and taught by his former PhD student (and our academic brother), the young Clark Colton.

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Stem cell-materials interactions themed issue now online

Graphical abstract: Front coverWe hope you enjoy reading our latest themed issue on stem cell—materials interactions, Guest Edited by Matthias Lutolf (EPFL) and Jason Burdick (University of Pennsylvania).

Stem cells have an enormous potential in regenerative medicine and drug discovery but the development of stem cell based therapies and models in these fields has been slow. This is largely due to the difficulty of maintaining functional stem cells in a culture dish or controlling their directed differentiation. Naturally, stem cells reside in highly complex microenvironments (termed ‘niches’) that regulate their behavior.

This themed issue focuses on emerging efforts to engineer these niches to better control and probe stem cell fate in culture and in vivo, including the development of new biomaterials, the better understanding of stem cell and biomaterial interfaces, and the implementation of biomaterials and bioreactors together.

Take a look at these themed issue highlights:

Nanotopography – potential relevance in the stem cell niche Lesley-Anne Turner and Matthew J. Dalby

Biophysical regulation of hematopoietic stem cells C. Lee-Thedieck and J. P. Spatz

Stem cell culture using cell-derived substrates Binata Joddar, Takashi Hoshiba, Guoping Chen and Yoshihiro Ito

Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture A. D. Celiz, J. G. W. Smith, A. K. Patel, R. Langer, D. G. Anderson, D. A. Barrett, L. E. Young, M. C. Davies, C. Denning and M. R. Alexander

Dual-stage growth factor release within 3D protein-engineered hydrogel niches promotes adipogenesis Midori Greenwood-Goodwin, Eric S. Teasley and Sarah C. Heilshorn

Artificial microniches for probing mesenchymal stem cell fate in 3DYujie Ma, Martin P. Neubauer, Julian Thiele, Andreas Fery and W. T. S. Huck

Download more articles here

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