Lectin-gold nanoparticle conjugate could aid understanding of relationship between cellular glycosylation machinery and cell function

Covalent coupling of proteins with gold nanoparticles creates robust and stable probes.

Scientists from China have synthesised a lectin-gold nanoparticle conjugate which can be used as an optical probe for evaluating glycosyl complexes on living cell surfaces.  Such information is invaluable for clinical biomarker research.

Read the paper for free until 30th August to learn more…

Synthesis and cell-surface binding of lectin-gold nanoparticle conjugates

Jine Wang, Dianjun Liu and Zhenxin Wang
Anal. Methods
DOI: 10.1039/C1AY05151B

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Technologies and strategies for glycoproteomics and glycomics and their application to clinical biomarker research

Fateme Tousi, William S. Hancock and Marina Hincapie
Anal. Methods, 2011, 3, 20-32
DOI: 10.1039/C0AY00413H

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