Archive for the ‘Covers 2013’ Category

Featured on the Covers of Issue 23

Stephenson-Brown et al., Analyst, 2013, 138, 7146-7151

We are delighted to highlight the latest covers of Analyst, showing new research on the development and application of a sensory system to detect glucose.

John Fossey from the University Birmingham, UK, and collaborators at the University of Bath, UK, and at the East China University of Science and Technology, China, present two papers describing a new glucose sensor based on the principle of self-assembly and surface plasmon resonance (SPR) optical technique.

Wang et al., Analyst, 2013, 138, 7146-7151

The sensor is prepared modifying the surface of a gold electrode with a bis-boronic acid receptor. The receptor contains a glucose selective chemosensor unit and a surface anchoring unit, which allows selective detection of glucose. This system has the unique capacity to label-free and allows detection of molecular reactions in real time with highly sensitivity. According to this research, SPR could be an attractive sensing platform to monitor glucose and possibly other analytes.

To read more about this work, please access the links below. These two papers are free to read, so have a look now:

A bis-boronic acid modified electrode for the sensitive and selective determination of glucose concentrations
Hui-Chen Wang, Hao Zhou, Baoqin Chen, Paula M. Mendes, John S. Fossey, Tony D. James and   Yi-Tao Long
Analyst, 2013, 138, 7146-7151
DOI: 10.1039/C3AN01234D

Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor
Alex Stephenson-Brown, Hui-Chen Wang, Parvez Iqbal, Jon A. Preece, Yitao Long, John S. Fossey, Tony D. James and   Paula M. Mendes 
Analyst, 2013, 138, 7140-7145
DOI: 10.1039/C3AN01233F

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Analyst Issue 12 now online

Fathi et al., Analyst, 2013, 138, 3380-3387

The new issue of Analyst is now available online! Here are three beautiful covers for you to enjoy.

The outside front cover features the work of Yi-Tao Long from the East China University of Science and Technology, Shanghai, and Heinz-Bernhard Kraatz from the University of Toronto Scarborough, Canada. In this study, the researchers show that modification of a nanostructured Ag surface with a porphyrin significantly enhances photocurrent compared to a monocrystalline Ag substrate.

Tailoring zinc porphyrin to the Ag nanostructure substrate: an effective approach for photoelectrochemical studies in the presence of mononucleotides
Farkhondeh Fathi, Cong Kong, Yueqiang Wang, Yongshu Xie, Yi-Tao Long and   Heinz-Bernhard Kraatz
Analyst, 2013,138, 3380-3387
DOI: 10.1039/C3AN00156C

Kumar et al., Analyst, 2013, 138, 3356-3359

Our inside front cover showcases research from the University of Delhi, India. Tarkeshwar Gupta and colleagues introduce a hitch-free fluorescent probe to monitor multiple-cations via differential responses using a single sensory system and a single transducing unit (emission spectroscopy).

A stimuli-responsive “smart probe” for selective monitoring of multiple-cations via differential analyses
Anup Kumar, Alok K. Singh and   Tarkeshwar Gupta
Analyst, 2013,138, 3356-3359
DOI: 10.1039/C3AN00087G

Jiang et al., Analyst, 2013, 138, 3388-3393

Finally, the inside back cover of this issue shows an image from a paper on the development of a new electrochemical immunosensor for Escherichia coli. Heyou Han and his group at the Huazhong Agricultural University, China, used a solid-state voltammetry with graphene oxide–Ag nanoparticle nanocomposites as labels, and successfully applied the biosensor for monitoring of E. coli in lake water.

Solid-state voltammetry-based electrochemical immunosensor for Escherichia coli using graphene oxide–Ag nanoparticle composites as labels
Xiaochun Jiang, Kun Chen, Jing Wang, Kang Shao, Tao Fu, Feng Shao, Donglian Lu, Jiangong Liang, M. Frahat Foda and   Heyou Han
Analyst, 2013,138, 3388-3393
DOI: 10.1039/C3AN00056G

In addition, here is an HOT article free for you to read until June 14th. To access the full paper, please click on the link below:

A miniaturised electron ionisation time-of-flight mass spectrometer that uses a unique helium ion removal pulsing technique specifically for gas analysis
Jiang Qing, Zhengxu Huang, Yan Zhang, Hui Zhu, Guobin Tan, Wei Gao and   Peng-yuan Yang 
Analyst, 2013,138, 3394-3401
DOI: 10.1039/C3AN00217A

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Analyst Issue 11 out now!

Wang and Schultz, Analyst, 2013, 138, 3150-3157

The latest issue of Analyst is now online and ready for you to enjoy. We have three new covers and a couple of HOT papers free for you to read.

On the outside cover is an image from a paper by Zachary Schultz and Hao Wang from the University of Notre Dame, USA, showing functionalised nanoparticles detected with surface-enhanced Raman scattering (SERS) and Tip-enhanced Raman scattering (TERS) using streptavidin and biotin as a model system for protein-ligand binding. The researchers examined the chemical origin of enhanced signals from SERS and TERS detection and observed that different sizes of functionalised nanoparticles show changes in intensities in both types of measurements.

The chemical origin of enhanced signals from tip-enhanced Raman detection of functionalized nanoparticles
Hao Wang and   Zachary D. Schultz  
Analyst, 2013,138, 3150-3157
DOI: 10.1039/C3AN36898J

Yun et al., Analyst, 2013, 138, 3196-3200

Our inside front cover features a study on digital imaging of cultured cells enhanced by augmented reality technologies. Won Gu Lee and colleagues from Seoul National University, South Korea, present a new method to look at specimens under the microscope using augmented indicators. This new technique enables observation of long term live cells and identification of the exact location of individual cells within a biological sample.

Microscopic augmented-reality indicators for long-term live cell time-lapsed imaging
Kyungwon Yun, Jungman Chung, Yong Park, Byungjoo Lee, Won Gu Lee and   Hyunwoo Bang  
Analyst, 2013,138, 3196-3200
DOI: 10.1039/C3AN00124E

Ishimoto et al., Analyst, 2013, 138, 3158-3162

Finally, our outisde back cover showcases research on the simplification of conventional neuraminidase inhibitor assays. Hideaki Hisamoto and his group at Osaka Prefecture University, Japan, successfully integrated the assay into a single step operation using a combinable poly(dimethylsiloxane) (PDMS) capillary sensor array.

Integration of neuraminidase inhibitor assay into a single-step operation using a combinable poly(dimethylsiloxane) capillary sensor
Tadashi Ishimoto, Kaede Jigawa, Terence G. Henares, Tatsuro Endo and   Hideaki Hisamoto  
Analyst, 2013,138, 3158-3162
DOI: 10.1039/C3AN36785A

Now take a look at the selected HOT papers below. They will be free to read until May 30th.

Tagging the rolling circle products with nanocrystal clusters for cascade signal increase in the detection of miRNA
Jingjing Yao, Kenneth Flack, Liangzi Ding and   Wenwan Zhong  
Analyst, 2013,138, 3121-3125
DOI: 10.1039/C3AN00398A

Isotachophoresis with ionic spacer and two-stage separation for high sensitivity DNA hybridization assay
Charbel Eid, Giancarlo Garcia-Schwarz and   Juan G. Santiago 
Analyst, 2013,138, 3117-3120
DOI: 10.1039/C3AN00374D

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Analyst Issue 10 now online

Woodin et al., Analyst, 2013, 138, 2793-2803

Welcome to Analyst Issue 10, our new issue featuring all the latest developments in analytical chemistry. Take a look at our beautiful covers and discover all about the new research behind them.

The outside front cover of the issue gives us a snapshot of the interesting Critical Review by Heather Desaire and co-authors at the University of Kansas, USA, who describe the most recent software tools designed for interpreting mass spectrometry data from glycans and glycopeptides. The authors describe how to analyse the composition of released glycans and characterise both N-linked and O-linked glycopeptides.

Software for automated interpretation of mass spectrometry data from glycans and glycopeptides
Carrie L. Woodin, Morgan Maxona and Heather Desaire
Analyst, 2013,138, 2793-2803
DOI: 10.1039/C2AN36042J

Patel et al., Analyst, 138, 2833-2839

Our inside front cover shows the work of Bhavik Anil Patel and colleagues at the University of Brighton, UK. The researchers fabricated and characterised a microelectrode array  for simultaneous multi-site recordings of dopamine release from an isolated single neuron. They observed electrically evoked dopamine release  from the cell body, axonal regions and the terminal. According to the authors, this study provides insights into the signalling mechanisms of neurons and formation of synaptic connections.

A planar microelectrode array for simultaneous detection of electrically evoked dopamine release from distinct locations of a single isolated neuron
Bhavik Anil Patel, Collin C. Luk, Pei Ling Leow, Arthur J. Lee, Wali Zaidic and Naweed I. Syedc  
Analyst, 2013,138, 2833-2839
DOI: 10.1039/C3AN36770C

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Analyst Issue 9 now online

Collins et al., Analyst, 2013, 138, 2540-2545

 Analyst Issue 9 is finally available online! Take a look at our great new covers and read all about the research behind them.

The outside front cover showcases research from the Dublin City University, Ireland. In this work, David Collins and colleagues present a non-invasive, in-process measurement of the layer growth during laminar flow polymerisation and discuss its application to existing methods for the fabrication of monoPLOT columns through both photo and thermal initiation.

In-process phase growth measurement technique in the fabrication of monolithic porous layer open tubular (monoPLOT) columns using capacitively coupled contactless conductivity
David A. Collins ,  Ekaterina P. Nesterenko ,  Dermot Brabazon and Brett Paull
Analyst, 2013,138, 2540-2545
DOI: 10.1039/C3AN00133D

Lai et al., Analyst, 2013, 138, 2598-2603

Our inside front cover shows the work of Jinhua Zhan and his team from the Shandong University in China. The researchers describe how SERS active extraction column-based on alkanethiols modified  silver dendrites facilitate analysis with high reliability and accuracy. According to the authors, this SERS-active extraction column combines the advantages of both SPE and SERS.

Combination of solid phase extraction and surface-enhanced Raman spectroscopy for rapid analysis
Yongchao Lai ,  Jingcheng Cui ,  Xiaohong Jiang ,  Sha Zhu and Jinhua Zhan
Analyst, 2013,138, 2598-2603
DOI: 10.1039/C3AN36700B

Tanaka et al., Analyst, 2013, 138, 2536-2539

Finally, the outside cover of this issue features interesting research on surface-enhanced photochromism. The study led by Kenta Adachi at Yamaguchi University shows the surface-enhanced photochromic phenomena by L-phenylalanine adsorbed on tungsten(VI) oxide (WO3) nanoparticles in the aqueous solution. The authors propose photochromic WO3 nanoparticles as highly effective colorimetric sensor probes for amino acids and related compounds.

Surface-enhanced photochromic phenomena of phenylalanine adsorbed on tungsten oxide nanoparticles: a novel approach for “label-free” colorimetric sensing
Shohei Tanaka ,  Kenta Adachi and Suzuko Yamazaki
Analyst, 2013,138, 2536-2539
DOI: 10.1039/C3AN36650B

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Analyst Issue 7 now online!

Analyst Issue 7 is now available online! Take a look at our new wonderful covers featuring the latest discoveries in the field of analytical chemistry.

Julia Laskin and her group used nanospray desorption electrospray ionization for spatial profiling of chemical gradients generated by microbial communities on plate, and detected metabolites and lipids on the colonies and the surrounding agar. This methodology, just featured on the outisde front cover of Issue 7, might facilitate future studies on interactions between bacterial colonies.

Spatially resolved analysis of glycolipids and metabolites in living Synechococcus sp. PCC 7002 using nanospray desorption electrospray ionization
Ingela Lanekoff ,  Oleg Geydebrekht ,  Grigoriy E. Pinchuk ,  Allan E. Konopka and Julia Laskin
Analyst, 2013,138, 1971-1978
DOI: 10.1039/C3AN36716A 

Our inside front cover shows the work of Ahu Arslan Yildiz and colleagues from the Institute of Material Research and Engineering in Singapore. The researchers analysed the human ether-à-go-go-related gene (hERG) potassium channel, which is known to be involved in inherited or drug-induced long QT syndrome. Surface Plasmon Fluorescence Spectroscopy and Imaging Surface Plasmon resonance techniques were used to investigate the interactions between hERG and the drug. According to the study, this new approach could be applied to other membrane proteins for drug screening or other prorein-related interactions.

Biomimetic membrane platform containing hERG potassium channel and its application to drug screening
Ahu Arslan Yildiz ,  CongBao Kang and Eva-Kathrin Sinner
Analyst, 2013,138, 2007-2012
DOI: 10.1039/C3AN36159D

Finally, our outside back cover presents the Tutorial Review written by Sergei Kazarian and Andrew Chan from Imperial College London, who outline the most recent advances and applications of attenuated total reflection Fourier transform infrared spectroscopy imaging in biomedical studies. In addition, future developments in the area are discussed. 

ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems
Sergei G. Kazarian and K. L. Andrew Chan
Analyst, 2013,138, 1940-1951
DOI: 10.1039/C3AN36865C

In addition, take a look below at our selected HOT articles of the issue. These papers will be free for you to enjoy until March 25th.

Facile formation of folic acid-modified dendrimer-stabilized gold–silver alloy nanoparticles for potential cellular computed tomography imaging applications
Hui Liu ,  Mingwu Shen ,  Jinglong Zhao ,  Jingyi Zhu ,  Tingting Xiao ,  Xueyan Cao ,  Guixiang Zhang and Xiangyang Shi
Analyst, 2013,138, 1979-1987
DOI: 10.1039/C3AN36649A

Label-free, disposable fiber-optic biosensors for DNA hybridization detection
Ming-jie Yin ,  Chuang Wu ,  Li-yang Shao ,  Wing Kin Edward Chan ,  A. Ping Zhang ,  Chao Lu and Hwa-yaw Tam
Analyst, 2013,138, 1988-1994
DOI: 10.1039/C3AN36791F

Novel switchable sensor for phosphate based on the distance-dependant fluorescence coupling of cysteine-capped cadmium sulfide quantum dots and silver nanoparticles
Guang-Li Wang ,  Huan-Jun Jiao ,  Xiao-Ying Zhu ,  Yu-Ming Dong and Zai-Jun Li
Analyst, 2013,138, 2000-2006
DOI: 10.1039/C3AN36878E

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Analyst Issue 6 NOW online

The new issue of Analyst is now available online. Take a look at our wonderful covers and discover all about the latest research behind them.

Our outside front cover shows the work of Igor Lednev and his group from the State University of New York, USA. The researchers analyse biological specimens using surface- and tip-enhanced Raman spectroscopy (SERS and TERS) and investigate the lack amide I band, commonly used as a marker for interpretation of the secondary protein structure.

Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens
Dmitry Kurouski ,  Thomas Postiglione ,  Tanja Deckert-Gaudig ,  Volker Deckert and Igor K. Lednev
Analyst, 2013,138, 1665-1673
DOI: 10.1039/C2AN36478F

Our interesting inside front cover showcases work from Luigi Sanguigno from the Italian Institute of Technology, who describes how fluorescence correlation spectroscopy (FCS) can be misleading in 2D systems. This study highlights the alignment issues and the effects of thermal fluctuations related to FCS in 2D systems and proposes elimination of systematic errors due to the misalignments of membranes.

Accounting for misalignments and thermal fluctuations in fluorescence correlation spectroscopy experiments on membranes
Luigi Sanguigno ,  Chiara Cosenza ,  Filippo Causa and Paolo Antonio Netti
Analyst, 2013,138, 1674-1681
DOI: 10.1039/C2AN36681A

The outside back cover of this issue introduces negative mode probe electrospray ionization mass spectrometry (PESI-MS) as a tool for biomolecular analysis and cancer dignostics. Mridul Kanti Mandal and colleagues from the University of Yamanashi, Japan, analysed several combinations of solvents and probes to optmise the conditions of ionization for biomolecules such as peptides, proteins and lipids.

Biomolecular analysis and cancer diagnostics by negative mode probe electrospray ionization
Mridul Kanti Mandal ,  Subhrakanti Saha ,  Kentaro Yoshimura ,  Yasuo Shida ,  Sen Takeda ,  Hiroshi Nonami and Kenzo Hiraoka
Analyst, 2013,138, 1682-1688
DOI: 10.1039/C3AN36554A

In addition, along with our new covers we also have some selected HOT articles for you to enjoy. These papers will be free to read for the next 10 days.

Take a look at Issue 6 now!

A mixed alkanethiol based immunosensor for surface plasmon field-enhanced fluorescence spectroscopy in serum
Andreas Scholten ,  Bernhard Menges ,  Martin Juebner ,  Markus A. Rothschild and Katja Bender
Analyst, 2013,138, 1705-1712
DOI: 10.1039/C3AN35657D

A Hg2+-mediated label-free fluorescent sensing strategy based on G-quadruplex formation for selective detection of glutathione and cysteine
Jingjin Zhao ,  Chunfei Chen ,  Liangliang Zhang ,  Jianhui Jiang ,  Guoli Shen and Ruqin Yu
Analyst, 2013,138, 1713-1718
DOI: 10.1039/C3AN36657J

Iodine excitation in a dielectric barrier discharge micro-plasma and its determination by optical emission spectrometry
Yong-Liang Yu ,  Shuai Dou ,  Ming-Li Chen and Jian-Hua Wang
Analyst, 2013,138, 1719-1725
DOI: 10.1039/C2AN36780G

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Analyst Issue 5 NOW online!

Analyst issue 5 has now gone online! Take a look at these three woderful covers and read all about the new discoveries behind them.

Featured on the outside front cover  is the recent study of Todd Mitchell and his group, from the University of Wollongong, Australia. The team describes a novel approach to identify lipids on the surface of contact lenses by using liquid extraction surface analysis coupled to tandem mass spectrometry, and shows that lipids can be extracted with limited degradation of the contact lenses in only 15 minutes.

Automated surface sampling of lipids from worn contact lenses coupled with tandem mass spectrometry
Simon H. J. Brown ,  Liam H. Huxtable ,  Mark D. P. Willcox ,  Stephen J. Blanksby and Todd W. Mitchell
Analyst, 2013,138, 1316-1320
DOI: 10.1039/C2AN36189B

Our inside front cover showcases work coming from the Republic of Korea. Taesung Kim and researchers at the Ulsan National Institute of Science and Technology introduce a surface-patterned Nafion film to induce ion concentration polarization. This method can be easily used for separation and concentration of proteins extracted from lysed bacterial cells simultaneously and continuously on a chip.

Ion concentration polarization in a single and open microchannel induced by a surface-patterned perm-selective film
Minseok Kim ,  Mingjie Jia and Taesung Kim
Analyst, 2013,138, 1370-1378
DOI: 10.1039/C2AN36346A

Finally, the interesting outisde back cover of this issue shows a novel strategy for efficient ionization of phosphopeptides in mixtures presented by Hao Chen and his group from the Ohio University, USA. Desorption electrospray ionization-mass spectrometry allows direct ionization of analytes without the need of sample separation or enrichment. The new method presented here would provide ionization and examination of analytes in low pH environment.

Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry
Ning Pan ,  Pengyuan Liu ,  Weidong Cui ,  Bo Tang ,  Jingmin Shi and Hao Chen
Analyst, 2013,138, 1321-1324
DOI: 10.1039/C3AN36737A

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Analyst Issue 4 NOW online!

Yu and White, Analyst, 2013, 138, 1020-1-25

The issue 4 of Analyst has now gone online! We have three beautiful covers showing new research coming from three different countries: China, Denmark and USA.

Castillo et al., Analyst, 2013, 138, 1026-1031

The outside front cover of this issue resembles the SERS-active paper dipsticks developed by Wei Yu and Ian White at the University of Maryland, USA. The paper-based devices fabricated by inkjet printing allow collection of analyte molecules from a liquid sample by simply dipping the paper into the sample. According to the authors, these paper dipsticks can be used to process much larger sample volumes than conventional SERS substrates.

Inkjet-printed paper-based SERS dipsticks and swabs for trace chemical detection
Wei W. Yu and Ian M. White
Analyst, 2013,138, 1020-1025
DOI: 10.1039/C2AN36116G

Our inside front cover offers a snapshot of Jaime Castillo-Leon‘s work, from the Technical University of Denmark. His study focuses on the development of a graphene-electrode modified with peptide nanotubes and folic acid to specifically detect  cervical cancer cells over-expressing folic acid. Application of this graphene-sensor to the diagnosis of other diseases where cells over-express folic acid is also discussed.

Detection of cancer cells using a peptide nanotube–folic acid modified graphene electrode
John J. Castillo ,  Winnie E. Svendsen ,  Noemi Rozlosnik ,  Patricia Escobar ,  Fernando Martínez and Jaime Castillo-León
Analyst, 2013,138, 1026-1031
DOI: 10.1039/C2AN36121C

Liang et al., Analyst, 2013, 138, 1032-1037

Finally, on the back cover is an image featuring a study led by Xiaohong Li and colleagues from the Beijing Normal University. In their paper, the researchers introduce an electrochemical hairpin DNA sensor which enables direct detection of the polycyclic aromatic hydrocarbon 9-hydroxyfluorene and they demonstrate efficient detection  in lake water.

Electrochemical detection of 9-hydroxyfluorene based on the direct interaction with hairpin DNA
Gang Liang ,  Xiaohong Li and Xinhui Liu
Analyst, 2013,138, 1032-1037
DOI: 10.1039/C2AN36255D

Nanoparticle-based immunoassays

In addition to our covers, here is an interesting minireview about recent developments of nanoparticle-based immunoassays in the biomedical field. Dianping Tang and and co-authors from the Fuzhou University in China outline the nanoparticle-based electrochemical, optical, colorimetric assays used so far and discuss future applications. To read the full article, please access the link below:

Nanoparticle-based immunoassays in the biomedical field
Dianping Tang ,  Yuling Cui and Guonan Chen
Analyst, 2013,138, 981-990
DOI: 10.1039/C2AN36500F

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Analyst Issue 3 NOW online!

Jacques et al., Analyst, 138, 755-759

The third issue of Analyst has now gone online with two beautiful covers for you to enjoy! Take a look at the innovative research behind them.

On the outside front cover we have an image from Simon Jacques, from the University of Manchester, who shows a new laboratory system for element specific hyperspectral X-ray imaging. This type of imaging can be used to separate and identify chemical species in bulk objects with no special sample, capturing X-rays and delivering directly 3D images. The method described has potential applications in material science, geology, security and medical science.

A laboratory system for element specific hyperspectral X-ray imaging
Simon D. M. Jacques, Christopher K. Egan, Matthew D. Wilson, Matthew C. Veale, Paul Seller and Robert J. Cernik
Analyst, 2013, 138, 755-759
DOI: 10.1039/C2AN36157D

McEwen et al., Analyst, 2013, 138, 787-797

Our inside front cover features the work from Anhong Zhou and his group from the Utah State University. The team explains how the development and application of Raman microspectroscopy and atomic force microscopy provide detailed information on cancer cells at the single cell and sub-cellular levels.

Subcellular spectroscopic markers, topography and nanomechanics of human lung cancer and breast cancer cells examined by combined confocal Raman microspectroscopy and atomic force microscopy
Gerald D. McEwen, Yangzhe Wu, Mingjie Tang, Xiaojun Qi, Zhongmiao Xiao, Sherry M. Baker, Tian Yu, Timothy A. Gilbertson, Daryll B. DeWald and Anhong Zhou
Analyst, 2013, 138, 787-797
DOI: 10.1039/C2AN36359C

Along with these new covers, take a look at the interesting review article written by Supreet Bahga and Juan Santiago on coupled isotachophoresis and capillary electrophoresis. Features, advantages, limitations, and optimization principles of the various methodologies are described in detail.

Coupling isotachophoresis and capillary electrophoresis: a review and comparison of methods
Supreet S. Bahga and Juan G. Santiago
Analyst, 2013, 138, 735-754
DOI: 10.1039/C2AN36150G

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