Surface enhancement can provide improved detection sensitivity in a range of optical spectroscopies.
Read this comprehensive review on surface enhanced optical spectroscopies and their application to bioanalysis by Analyst Editorial Board member Duncan Graham and his colleague Iain Larmour. They consider the “grand challenges” that need to be overcome before widespread clinical use of surface enhanced techniques can be achieved.
The review will be free until the 6th September.
Surface enhanced optical spectroscopies for bioanalysis
Iain A. Larmour and Duncan Graham
This paper is part of an ongoing collection of articles looking at Grand Challenges in analytical science. In celebration of the International Year of Chemistry, leading scientists (including our own Board members) have put together papers outlining the current challenges faced in analytical science, and how these might be tackled, some of which were published in issue 15.
Below are a selection of recent Analyst papers mentioned in the review:
Evaluation of tip-enhanced Raman spectroscopy for characterizing different virus strains
Peter Hermann, Antje Hermelink, Veronika Lausch, Gudrun Holland, Lars Möller, Norbert Bannert and Dieter Naumann
Analyst, 2011, 136, 1148-1152
Surface enhanced Raman evidence for Ag+ complexes of adenine, deoxyadenosine and 5′-dAMP formed in silver colloids
Evanthia Papadopoulou and Steven E. J. Bell
Analyst, 2010, 135, 3034-3037
Competitive surface-enhanced Raman scattering assay for the 1,25-dihydroxy metabolite of vitamin D3
Eric J. Dufek, Brian Ehlert, Michael C. Granger, Tanya M. Sandrock, Samuel L. Legge, Mark G. Herrmann, A. Wayne Meikle and Marc D. Porter
Analyst, 2010, 135, 2811-2817
Short-wave infrared excited SERS
Kirstin A. Lynn, Graeme McNay, David A. Eustace, Neil C. Shand and W. Ewen Smith
Analyst, 2010, 135, 1904-1905