Antibiotics pit against bacterial biofilms

Written by Harriet Brewerton for Chemistry World

Graphical AbstractScientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics.

Monitoring bacterial growth is important for rapidly treating infections with the lowest effective concentration of antibiotics. The effectiveness of antibiotics is traditionally tested by adding patient samples to antibiotic mixtures then visually inspecting the antibiotic growth. However, this method requires large amounts of reagents and does not consider the effect of antibiotics on the bacterial biofilm.

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Thaddaeus A. Webster, Hunter J. Sismaet, I-ping J. Chan and Edgar D. Goluch
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01358E, Paper

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