Archive for April, 2013

The 36th Annual Meeting of the Brazilian Chemical Society – Aguas de Lindoia, Brazil 25-28 May 2013

The 36th Annual Meeting of the Brazilian Chemical Society is being held this month in Aguas de Lindoia, Brazil, 25th-28th May. Click here for more information.

Analyst and Analytical Methods are pleased to announce a cross journal web-themed issue on Analytical Sciences in Brazil. Interdisciplinary analytical science is particularly welcome. Guest Editor Ivo M. Raimundo Jr. will be in attendance at the Brazilian Chemical Society annual meeting.

Submission deadline: 31st Jan 2014
Articles published online in a web collection

Guest Editors: Boris Mizaikoff, University of Ulm
Ivo M. Raimundo Jr., UNICAMP

For more information please contact analyst-rsc@rsc.org

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New Hot Articles in Analyst

Synthesis, characterisation, tomography imaging of bismuth sulfide nanoparticles

Take a look at our HOT papers now available online . Tomography imaging applications, serum micro-Raman spectroscopy and photoelectrochemical studies are among the topics featured in these articles.

To read the full papers, please access the links below. They will be free for you until  May 20th.

Dendrimer-stabilized bismuth sulfide nanoparticles: synthesis, characterization, and potential computed tomography imaging applications
Yi Fang, Chen Peng, Rui Guo, Linfeng Zheng, Jinbao Qin, Benqing Zhou, Mingwu Shen, Xinwu Lu, Guixiang Zhang and   Xiangyang Shi  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00237C

Diagnosis of hepatocellular carcinoma in cirrhotic patients: a proof-of-concept study using serum micro-Raman spectroscopy
I. Taleb, G. Thiéfin, C. Gobinet, V. Untereiner, B. Bernard-Chabert, A. Heurgué, C. Truntzer, P. Hillon, M. Manfait, P. Ducoroyc and   G. D. Sockalingum  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00245D

Carbon nanotubes biosensors for malondialdehyde detection

Tagging the rolling circle products with nanocrystal clusters for cascade signal increase in the detection of miRNA
Jingjing Yao, Kenneth Flack, Liangzi Ding and   Wenwan Zhong
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00398A

Label-free and facile electrochemical biosensing using carbon nanotubes for malondialdehyde detection
Ling Yuan, Yaqian Lan, Min Han, Jianchun Bao, Wenwen Tu and   Zhihui Dai
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00041A

Tailoring zinc porphyrin to the Ag nanostructure substrate: an effective approach for photoelectrochemical studies in the presence of mononucleotides
Farkhondeh Fathi, Cong Kong, Yueqiang Wang, Yongshu Xie, Yi-Tao Long and   Heinz-Bernhard Kraatz  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00156C

Isotachophoresis with ionic spacer and two-stage separation for high sensitivity DNA hybridization assay
Charbel Eid, Giancarlo Garcia-Schwarz and   Juan G. Santiago 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00374D

Biological and biomedical 14C-accelerator mass spectrometry and graphitization of carbonaceous samples
Ill-Min Chung and   Seung-Hyun Kim
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00077J

An AC electrokinetics facilitated biosensor cassette for rapid pathogen identification
Mengxing Ouyang, Ruchika Mohan, Yi Lu, Tingting Liu, Kathleen E. Mach, Mandy L. Y. Sin, Mason McComb, Janhvi Joshi, Vincent Gau, Pak Kin Wong and   Joseph C. Liao 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00259D

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Quicker checks for safer water

Scientists in the Netherlands have developed and tested a new method that uses Raman spectroscopy to quickly identify harmful bacteria in drinking water. This could prevent contaminated drinking water from making people ill by detecting deadly bacteria before it ever reaches the tap.

Many of the standard methods used to test water quality rely on selective plating and enzyme activity tests which take a long time to get results. ‘The bottleneck between collection and results is because microbes need time to grow, or nucleic acids need time to be processed,’ says Jack van de Vossenberg, from the KWR Watercycle Research Institute, who led the research.

To read the full article please visit Chemistry World.

Identification of bacteria in drinking water with Raman spectroscopy
Jack van de Vossenberg, Heli Tervahauta, Kees Maquelin, Carola H. W. Blokker-Koopmans, Marijan Uytewaal-Aarts, Dick van der Kooij, Annemarie van Wezel and Bram van der Gaag  
Anal. Methods, 2013, Accepted Manuscript
DOI: 10.1039/C3AY40289D

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DNA, Russian opera and blue suede shoes

Duncan Graham is Professor of chemistry at the University of Strathclyde, UK. He has recently been named as the next Chair of the Editorial Board for Analyst, and will start this role in 2014. His research areas include nucleic acid chemistry and synthetic chemistry for bioanalysis. Currently he is working on functionalised metallic nanoparticles that can be used for the diagnosis and treatment of disease.

What motivated you to specialise in SERS (surface enhanced Raman spectroscopy)?

Duncan Graham

 To read the full article please visit Chemistry World.

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Probing Alzheimer’s disease Plaques using Synchrotron FTIR

Visible and FTIR images showing plaques and lipids in mice tissues

Alzheimer’s disease (AD) affects millions of patients worldwide, and with much still unknown, few treatments options are available for the long duration of this disease. Although opinions differ on the cause of AD, histological staining shows the presence of neurotoxic plaques and tangles in deceased patients and serves as the primary diagnostic method.

Researchers at the University of Manitoba, Canada, used high resolution Fourier Transform Infrared Spectroscopy (FTIR) to image brain tissue in mice and human samples in order to study plaque formation at the sub cellular level. Different components in the cell such as DNA, proteins or sugars, produce unique chemical signatures which correspond to vibrational bands. The researchers discovered infiltration of lipid membrane components surrounding the plaques, which increase the signal as the plaques become larger. The spatial resolution of the system used here enables detection of lipids that a staining would miss, but it is important to understand disease progression. Although the relationship between plaque formation and lipid concentration remains unclear, the authors have developed a new method towards understanding plaque formation in AD.

To read the full article, please access the link below. This paper will be free to read until May 14th .

Synchrotron FTIR reveals lipid around and within amyloid plaques in transgenic mice and Alzheimer’s disease brain
Catherine R. Liao, Margaret Rak, Jillian Lund, Miriam Unger, Eric Platt, Benedict C. Albensi, Carol J. Hirschmugl and   Kathleen M. Gough
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00295K

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HOT papers in Analyst Issue 10

Enjoy our new HOT papers free for you to read until May 15th. Click on the links below:

Analyst Issue 10

Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay
Lenka Veverková, Kamil Zárubaa and   Vladimír Král
Analyst, 2013,138, 2804-2807
DOI: 10.1039/C3AN36760F

LED-induced in-column molecular imprinting for solid phase extraction/capillary electrophoresis
Xinfeng Zhang, Shuxia Xu, Yong-Ill Lee and   Steven A. Soper
Analyst, 2013,138, 2821-2824
DOI: 10.1039/C3AN00257H

Radical induced disulfide bond cleavage within peptides via ultraviolet irradiation of an electrospray plume
Craig A. Stinson and   Yu Xia
Analyst, 2013,138, 2840-2846
DOI: 10.1039/C3AN00303E

Detection of factor IX using PEG-based blocking agents

A dual channel optical detector for trace water chemodosimetry and imaging of live cells
Guangwen Men, Guirong Zhang, Chunshuang Liang, Huiling Liu, Bing Yang, Yuyu Pan, Zhenyu Wang and   Shimei Jiang
Analyst, 2013,138, 2847-2857
DOI: 10.1039/C3AN36887D

An in situ spatially resolved analytical technique to simultaneously probe gas phase reactions and temperature within the packed bed of a plug flow reactor
Jamal Touitou, Robbie Burch, Christopher Hardacre, Colin McManus, Kevin Morgan, Jacinto Sá and   Alexandre Goguet
Analyst, 2013,138, 2858-2862
DOI: 10.1039/C3AN00250K

A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity
Thangavel Lakshmipriya, Makoto Fujimaki, Subash C. B. Gopinath, Koichi Awazu, Yukichi Horiguchi and   Yukio Nagasaki  
Analyst, 2013,138, 2863-2870
DOI: 10.1039/C3AN00298E

Probing site-exclusive binding of aqueous QDs and their organelle-dependent dynamics in live cells by single molecule spectroscopy
Chaoqing Dong, Basudev Chowdhury and   Joseph Irudayaraj 
Analyst, 2013,138, 2871-2876
DOI: 10.1039/C3AN36906D

A thin-layered chromatography plate prepared from naphthalimide-based receptor immobilized SiO2 nanoparticles as a portable chemosensor and adsorbent for Pb2+
Sunhong Park, Jin Hyeok Lee and   Jong Hwa Jung  
Analyst, 2013,138, 2812-2815
DOI: 10.1039/C3AN00292F

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RSC Grants for the 44th IUPAC World Chemistry Congress

£400 bursaries for ten UK-based PhD student and early career researcher members provided by the RSC to participate in the 44th IUPAC World Chemistry Congress in Istanbul, Turkey, 11-16 August 2013.

 

The main topic of this year’s congress is “Clean Energy Through Chemistry”. Speakers include Daniel Nocera from Harvard and Martin Quack from ETH Zurich. For more details, please see http://www.iupac2013.org/.

To apply for this grant, please complete the application form (my.rsc.org/content/images/Science/IUPAC-application.pdf) and include a copy of your CV by noon on Friday the 26th April. Applications should be sent to science@rsc.org.

Please note that the registration deadline for IUPAC 2013 is the 30th April.  Members wishing to apply for an RSC grant will also need to register for the congress via the IUPAC 2013 website (http://www.iupac2013.org/abstract_submissions.asp).

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Analyst Issue 10 now online

Woodin et al., Analyst, 2013, 138, 2793-2803

Welcome to Analyst Issue 10, our new issue featuring all the latest developments in analytical chemistry. Take a look at our beautiful covers and discover all about the new research behind them.

The outside front cover of the issue gives us a snapshot of the interesting Critical Review by Heather Desaire and co-authors at the University of Kansas, USA, who describe the most recent software tools designed for interpreting mass spectrometry data from glycans and glycopeptides. The authors describe how to analyse the composition of released glycans and characterise both N-linked and O-linked glycopeptides.

Software for automated interpretation of mass spectrometry data from glycans and glycopeptides
Carrie L. Woodin, Morgan Maxona and Heather Desaire
Analyst, 2013,138, 2793-2803
DOI: 10.1039/C2AN36042J

Patel et al., Analyst, 138, 2833-2839

Our inside front cover shows the work of Bhavik Anil Patel and colleagues at the University of Brighton, UK. The researchers fabricated and characterised a microelectrode array  for simultaneous multi-site recordings of dopamine release from an isolated single neuron. They observed electrically evoked dopamine release  from the cell body, axonal regions and the terminal. According to the authors, this study provides insights into the signalling mechanisms of neurons and formation of synaptic connections.

A planar microelectrode array for simultaneous detection of electrically evoked dopamine release from distinct locations of a single isolated neuron
Bhavik Anil Patel, Collin C. Luk, Pei Ling Leow, Arthur J. Lee, Wali Zaidic and Naweed I. Syedc  
Analyst, 2013,138, 2833-2839
DOI: 10.1039/C3AN36770C

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HOT articles in Analyst

Chemical interactions and fate of nanoprobes upon entering living cells

Take a look at our new HOT papers free for you to read until May 13th !

Do you know what happens to nanoprobes once they enter living cells? And did you hear about  in-column molecularly imprinted solid phase extraction concentrators for capillary electrophoresis?

To know more about the latest research published in Analyst, click on the links below and enjoy the reading!

LED-induced in-column molecular imprinting for solid phase extraction/capillary electrophoresis
Xinfeng Zhang ,  Shuxia Xu ,  Yong-Ill Lee and Steven A. Soper
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00257H

New light emitting diode polymerization technology

A thin-layered chromatography plate prepared from naphthalimide-based receptor immobilized SiO2 nanoparticles as a portable chemosensor and adsorbent for Pb2+
Sunhong Park ,  Jin Hyeok Lee and Jong Hwa Jung
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00292F

Off-line reaction monitoring of the oxidation of alkenes in water using drop coating deposition Raman (DCDR) spectroscopy
Shaghayegh Abdolahzadeh ,  Nicola M. Boyle ,  Apparao Draksharapu ,  Andrew C. Dennis ,  Ronald Hage ,  Johannes W. de Boer and Wesley R. Browne
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00330B

Probing site-exclusive binding of aqueous QDs and their organelle-dependent dynamics in live cells by single molecule spectroscopy
Chaoqing Dong,a   Basudev Chowdhurya and   Joseph Irudayaraj*a  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36906D

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Top ten most accessed articles in February

This month sees the following articles in Analyst that are in the top ten most accessed:-

Lipid imaging by mass spectrometry – a review 
David Godea, Dietrich A. Volmer 
Analyst, 2013,138, 1289-1315 
DOI: 10.1039/C2AN36337B  

Carbon nanotube immobilized polar membranes for enhanced extraction of polar analytes 
Madhuleena Bhadraa and Somenath Mitra 
Analyst, 2012,137, 4464-4468 
DOI: 10.1039/C2AN35619H  

Antibody orientation on biosensor surfaces: a minireview 
Anke K. Trilling, Jules Beekwildera and Han Zuilhof 
Analyst, 2013,138, 1619-1627 
DOI: 10.1039/C2AN36787D  

A novel near-infrared fluorescent probe for selectively sensing nitroreductase (NTR) in an aqueous medium 
Youmin Shi, Sichun Zhang and Xinrong Zhang 
Analyst, 2013,138, 1952-1955 
DOI: 10.1039/C3AN36807F  

Protein amyloids develop an intrinsic fluorescence signature during aggregation 
Fiona T. S. Chan, Gabriele S. Kaminski Schierle, Janet R. Kumita,  Carlos W. Bertoncini, Christopher M. Dobson and Clemens F. Kaminski 
Analyst, 2013,138, 2156-2162 
DOI: 10.1039/C3AN36798C  

Fabrication of Cr doped SnO2 nanoparticles based biosensor for the selective determination of riboflavin in pharmaceuticals 
N. Lavanya, S. Radhakrishnan, C. Sekar, M. Navaneethanb and Y. Hayakawa 
Analyst, 2013,138, 2061-2067 
DOI: 10.1039/C3AN36754A  

A quantum dot-based “off–on” fluorescent probe for biological detection of zinc ions 
Hu Xu, Zhiping Wang, Yan Li, Shijian Ma, Peiyi Hua and Xinhua Zhong 
Analyst, 2013,138, 2181-2191 
DOI: 10.1039/C3AN36742H  

Upconversion nanoparticles in biological labeling, imaging, and therapy 
Feng Wang, Debapriya Banerjee, Yongsheng Liu, Xueyuan Chenc and Xiaogang Liu 
Analyst, 2010,135, 1839-1854 
DOI: 10.1039/C0AN00144A  

Rayleigh, Ramsay, Rutherford and Raman – their connections with, and contributions to, the discovery of the Raman effect 
Robin J. H. Clark 
Analyst, 2013,138, 729-734 
DOI: 10.1039/C2AN90124B  

Protein lysine acetylation analysis: current MS-based proteomic technologies 
Kai Zhang, Shanshan Tianab and Enguo Fan 
Analyst, 2013,138, 1628-1636 
DOI: 10.1039/C3AN36837H  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Analyst? Then why not submit to us today or alternatively email us your suggestions.

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