Analyst Blog

Here are some great HOT articles for you free to read until January 24th!

Topics include improved detection methodologies such as aptamer-based spectrofluorometry for cellular prion protein detection and new signal-amplified strategies to detect chair-like antiparallel G-quadruplex. In addition, an interesting study from Germany presents a new versatile reactor design developed for monitoring multiphase reactions. Take a look at the full articles below:

Comprehensive monitoring of a biphasic switchable solvent synthesis
Sonja Hardy ,  Irene M. de Wispelaere ,  Walter Leitner and Marcel A. Liauw
Analyst, 2013,138, 819-824
DOI: 10.1039/C2AN36044F

Aptamer-based spectrofluorometry for cellular prion protein using N,N′-bis[3,3′-(dimethylamino)propylamine]-3,4,9,10-perylenetetracarboxylic diimide
Lei Zhan ,  Li Jiao Liang ,  Shu Jun Zhen ,  Chun Mei Li and Cheng Zhi Huang
Analyst, 2013,138, 825-830
DOI: 10.1039/C2AN36322D

New reactor based on UV-Vis and mIR ATR-spectroscopy

Enzyme-free colorimetric bioassay based on gold nanoparticle-catalyzed dye decolorization
Wei Li ,  Jie Li ,  Weibing Qiang ,  Jingjuan Xu and Danke Xu
Analyst, 2013,138, 760-766
DOI: 10.1039/C2AN36374G

A novel signal-amplified strategy based on assembly reactivation for highly specific and sensitive detection of chair-like antiparallel G-quadruplex
Wei Gai ,  Qianfan Yang ,  Junfeng Xiang ,  Wei Jiang ,  Qian Li ,  Hongxia Sun ,  Lijia Yu ,  Qian Shang ,  Aijiao Guan ,  Hong Zhang and Yalin Tang
Analyst, 2013,138, 798-804
DOI: 10.1039/C2AN36557J

Comparison of photo- and Cu(I)-catalyzed “click” chemistries for the formation of carbohydrate SPR interfaces
Nazek Maalouli ,  Alexandre Barras ,  Aloysius Siriwardena ,  Mohamed Bouazaoui ,  Rabah Boukherroub and Sabine Szunerits
Analyst, 2013,138, 805-812
DOI: 10.1039/C2AN36272D

A highly selective fluorescent probe for BO₃⁻ based on acetate derivatives of coumarin in aqueous solution and thimerosal
Fangjun Huo ,  Long Wang ,  Yutao Yang ,  Yueyin Chu ,  Caixia Yin ,  Jianbin Chao ,  Yongbin Zhang ,  Xuxiu Yan ,  Anmin Zheng ,  Shuo Jin and Peng Zhi
Analyst, 2013,138, 813-818
DOI: 10.1039/C2AN36492A

A new MTS Search Engine has been recently optimised to identify volatile compounds such as pesticides, pollutants and nitrosamines.
The mass to structure or MTS Search Engine is a database containing theoretical molecular mass information for about 20,000 compounds and it was initially developed for identification of compounds in atmospheric pressure ionization (API)-LC-MS. The database can be used for forensic studies and allows determination of street drugs, doping agents in urine samples and determination of pesticides in food. So far, it has been used exclusively for non-volatile analytes determined by LC-MS.

MTS Search Engine based on GC-MS spectra

Wenta Liao and William Draper from USA now extend the identification to volatile and semi-volatile compounds using chemical ionization GC-MS. According to the authors, this new MTS Search Engine has the advantage to identify a wide variety of pesticides, nitrosamines and other toxic substances, as well as halogenated and non-halogenated structures, which could not be identified before.

To read more about this research, take a look at the full article by clicking the link below. This paper will be free to read until January 24th.

Identification of volatile and semivolatile compounds in chemical ionization GC-MS using a Mass-To-Structure (MTS) Search Engine with integral isotope pattern ranking
Wenta Liao and William M. Draper
Analyst, 2013, Advance Article
DOI: 10.1039/C2AN36490E