Analyst, 2011, 136(20):4085-4368
Optical analysis features on both covers of our latest issue.
On the front cover, Kagan Kerman of the University of Toronto and colleagues used near-IR optical trapping to characterise the early stages of aggregation of amyloid-beta (Aβ) peptides, an indicator of Alzheimer’s disease. The work provides new insight into the first two hours of aggregation, and therefore our understanding of the role of Aβ oligomers in neuronal cell cytotoxicity and pathogenesis.
Optical trapping for the characterization of amyloid-beta aggregation kinetics
Anthony J. Veloso, Hiroyuki Yoshikawa, Xin R. Cheng, Eiichi Tamiya and Kagan Kerman
Analyst, 2011, 136, 4164-4167
DOI: 10.1039/C1AN15480J
On the back cover, Tarkeshwar Gupta and Anup Kumar demonstrate direct label free optical detection of parts-per-billion (ppb) levels of Fe(II) in an organic solvent. Molecular recognition at solid–solution or solid–gas interfaces has received tremendous scientific interest to develop nanoscale molecular systems for chemical sensors, molecular switches and logic architectures.
Communication: A highly sensitive redox-active monolayer for “signal-on” optical detection of iron(II)
Tarkeshwar Gupta and Anup Kumar
Analyst, 2011, 136, 4127-4129
DOI: 10.1039/C1AN15519A
Both articles are free for 6 weeks, so do take a look!
