Read this communication by Stefan Glöggler and colleagues on an application of low-field NMR combined with Signal Amplification by Reversible-Exchange (SABRE) to detect traces of drugs. They were able to selectively enhance the signal of drug molecules in proton rich standard solutions that would otherwise mask the 1H NMR signal of the drug.
The article will be free to access until the 18th March. How do you think mobile NMR machines will be used for trace drug detection and differentiation in the future? Leave your comments below or tweet us @analystrsc.
Selective drug trace detection with low-field NMR
Stefan Glöggler, Meike Emondts, Johannes Colell, Rafael Müller, Bernhard Blümich and Stephan Appelt
Analyst, 2011
DOI: 10.1039/C0AN01048K
